Xuan, Fang-Ling and Chithanathan, Keerthana and Lilleväli, Kersti and Yuan, Xiaodong and Tian, Li (2019) Differences of Microglia in the Brain and the Spinal Cord. Frontiers in Cellular Neuroscience, 13. ISSN 1662-5102
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Abstract
Microglia were previously regarded as a homogenous myeloid cell lineage in the mammalian central nervous system (CNS). However, accumulating evidences show that microglia in the brain and SC are quite different in development, cellular phenotypes and biological functions. Although this is a very interesting phenomenon, the underlying mechanisms and its significance for neurological diseases in association with behavioral and cognitive changes are still unclear. How microglia differ between these two regions and whether such diversity may contribute to CNS development and functions as well as neurological diseases will be discussed in this Perspective.
Item Type: | Article |
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Subjects: | Science Repository > Medical Science |
Divisions: | Faculty of Engineering, Science and Mathematics > School of Civil Engineering and the Environment |
Depositing User: | Managing Editor |
Date Deposited: | 25 May 2023 11:13 |
Last Modified: | 07 Dec 2023 03:35 |
URI: | http://research.manuscritpub.com/id/eprint/2306 |