Dementia and Diabetes Mellitus in Porto-Novo: Frequency and Determining Factors

Wanvoegbe, Finangnon Armand and Gnonlonfoun, Dieu Donne and Agbodande, Kouessi Anthelme and Fandi, Arnaulde Amoussou-Guenou and Gnanguenon, Muriel Bernice and Azon-Kouanou, Angèle and Adjien, Constant and Amoussou-Guenou, Daniel and Zannou, Djimon Marcel and Houinato, Dismand (2021) Dementia and Diabetes Mellitus in Porto-Novo: Frequency and Determining Factors. Open Journal of Internal Medicine, 11 (04). pp. 246-257. ISSN 2162-5972

[thumbnail of ojim_2021122314325032.pdf] Text
ojim_2021122314325032.pdf - Published Version

Download (624kB)


Background: Chronic hyperglycemia promotes the development of degenerative diseases such as dementia. Our objective is to study dementia in diabetic patients in a hospital environment in Porto-Novo. Methods: This is a cross-sectional, prospective study with a descriptive and analytical aim that took place from May 18 to September 18, 2017, i.e. 4 months. The study population consists of all diabetic patients who consulted in the internal medicine departments of the Oueme-Plateau Teaching Hospital and at Saint Gérard clinic in Porto-Novo during the study period and who gave their enlightened consent. Results: The study included 246 patients with a mean age of 56.47 ± 11.97 years. There were 172 (69.9%) women, i.e. a sex ratio of 0.43. Diabetes had been known for less than 10 years in the majority (67.9%). Type 2 diabetics were in the majority (95.5%). Of the 246 patients, 42 (17.1%) had a Mini Mental State Examination (MMSE) less than or equal to 24. Of these 42 patients, 32 met the DSM V (Diagnostic and Statistical Manual disorders, 5th edition) criteria for dementias, i.e. a frequency of 13.0%. Of the 32 demented patients, 21 (65.6%) had vascular dementia and 34.4% had degenerative dementia. We did not note a mixed etiology. Dementia was severe in 15.6% of cases. In multivariate analysis, only age (OR = 10.09; 95% CI [4.19 - 24.27]; p < 0.001), arterial hypertension (OR = 7.10; 95% CI [1.92 - 26.22]; p = 0.003), and alcohol consumption (OR = 3.95; 95% CI [1.29 - 12.15]; p = 0.017) were statically associated with the onset of dementia in our diabetic patients. Conclusion: Screening for dementia should be systematic in diabetics, especially at old age.

Item Type: Article
Subjects: Science Repository > Medical Science
Depositing User: Managing Editor
Date Deposited: 07 Jun 2023 04:22
Last Modified: 08 Nov 2023 08:07

Actions (login required)

View Item
View Item