The First Synthesis of Sessiline

Ilkei, Viktor and Faragó, Kornél and Sánta, Zsuzsanna and Dékány, Miklós and Hazai, László and Szántay Jr., Csaba and Szántay, Csaba and Kalaus, György (2014) The First Synthesis of Sessiline. International Journal of Organic Chemistry, 04 (05). pp. 309-313. ISSN 2161-4687

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Official URL: https://doi.org/10.4236/ijoc.2014.45033

Abstract

Sessiline is an alkaloid which is recently isolated from the fruits of Acanthopanax sessiliflorus. The molecule contains two five-membered heterocyclic units joined together by an acylaminocarbinol-ether type bond. Here, we describe the first, simple synthesis of sessiline from 5-hydroxypyrrolidin-2-one and 5-hydroxymethylfurfural, which are prepared from succinimide and furfuryl alcohol, respectively. The coupling reaction takes place on moderate heating under neat conditions.

Item Type:	Article
Subjects:	Science Repository > Chemical Science
Depositing User:	Managing Editor
Date Deposited:	04 Feb 2023 04:32
Last Modified:	07 Jun 2024 09:33
URI:	http://research.manuscritpub.com/id/eprint/1234

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