Yamaguchi, Jun-Ichi and Shibuta, Emiko and Oishi, Yoshie (2014) Simple Reduction of Hydantoins with Sodium Borohydride. International Journal of Organic Chemistry, 04 (05). pp. 286-291. ISSN 2161-4687
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Official URL: https://doi.org/10.4236/ijoc.2014.45031
Abstract
The reduction of various hydantoins with sodium borohydride gave the corresponding 4-hydroxy- 2-imidazolidinones in high yields. In contrast, reduction employing a boron trifluoride etherate-sodium borohydride system generated 2-imidazolidinones. In both reductions, the reactivity of the hydantoin was dependent on its substituents. The Lewis acid-promoted reactions of a 4-hydroxy-2-imidazolidinone with nucleophiles were also investigated.
| Item Type: | Article |
|---|---|
| Subjects: | Science Repository > Chemical Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 19 Jan 2023 09:07 |
| Last Modified: | 07 Jun 2024 09:33 |
| URI: | http://research.manuscritpub.com/id/eprint/1292 |
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