11C-Labeling of the C(1)-C(10) Dihydroxy Acid Moiety for the Study on the Synthesis of Kulokekahilide-2 PET Tracer

Han, Chunguang and Doi, Hisashi and Kimura, Junji and Nakao, Yoichi and Suzuki, Masaaki (2014) 11C-Labeling of the C(1)-C(10) Dihydroxy Acid Moiety for the Study on the Synthesis of Kulokekahilide-2 PET Tracer. International Journal of Organic Chemistry, 04 (04). pp. 269-277. ISSN 2161-4687

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Official URL: https://doi.org/10.4236/ijoc.2014.44029

Abstract

11C-labeled C1-C10 partial structure of kulokekahilide-2 (1) was successfully synthesized based on Pd0-mediated rapid C-[11C]methylation using [11C]methyl iodide and pinacol alkenylboronate. The preparation of organoboron intermediate via olefin cross-metathesis is also a crucial procedure for the synthesis of 11C-labeling C1-C10 dihy-droxy acid moiety of 1.

Item Type:	Article
Subjects:	Science Repository > Chemical Science
Depositing User:	Managing Editor
Date Deposited:	21 Jan 2023 04:52
Last Modified:	30 May 2024 06:21
URI:	http://research.manuscritpub.com/id/eprint/1298

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