Nchejane, J. N. and Gbenro, S. O. and Thakedi, M. E. (2022) Numerical Simulation of the Evolution of Wound Healing in the 3D Environment. Journal of Advances in Mathematics and Computer Science, 37 (4). pp. 20-30. ISSN 2456-9968
![[thumbnail of 1655-Article Text-3222-1-10-20221012.pdf]](http://research.manuscritpub.com/style/images/fileicons/text.png)
1655-Article Text-3222-1-10-20221012.pdf - Published Version
Download (725kB)
Abstract
Numerical simulation of the wound healing behaviour by considering the coupled reaction-diffusion, transport and viscoelastic system is vital in investigating the mechanical stress field induced by cell migration. In this work, numerical simulation is viewed in three-dimensional space during a time course of wound healing. Over the years, many authors have developed two-dimensional mathematical models of wound healing, as supported by the background in the introduction below. But we know that a three-dimensional case realistically captures the tissue deformations. The two-dimensional simulation is restricted to observing the motion in two directions only. Hence, the interest is in the three-dimensional case. Therefore, to our knowledge, this is the first article to consider the numerical simulation of the coupled reaction-diffusion, transport and viscoelastic system during wound healing in a three-dimensional environment. Firstly, the two-dimensional evolution of wound healing is developed to compare our results with published data. Then the work is extended to three-dimensional wound healing, which is the main focus.
Item Type: | Article |
---|---|
Subjects: | Science Repository > Mathematical Science |
Depositing User: | Managing Editor |
Date Deposited: | 17 Feb 2023 06:26 |
Last Modified: | 19 Jun 2024 11:35 |
URI: | http://research.manuscritpub.com/id/eprint/1479 |