A Study of Improvement of Left Ventricle Ejection Fraction in Heart Failure Patients with Reduced Ejection Fraction with Coronary Artery Diseases after Revascularization by Percutaneous Coronary Intervention (PCI)

Background: Left ventricular dysfunction is the single strongest predictor of mortality and one of the most frequent and deadly complication following coronary artery diseases.

Aim: This work aims to study and explore the left ventricle ejection fraction improvement after revascularization with percutaneous coronary intervention (PCI) and the predictive factors for left ventricle ejection fraction improvement.

Methods: One hundred patients with ischemic (HFrEF) who had complete revascularization with percutaneous coronary intervention (PCI), had survived at least 90 days and had undergone echocardiography review. The study duration was 1 year from April 2019 to May 2020.

Result: We focused on a group of the common possible predictive factors affecting left ventricular improvement. Gender (male), CKD, DM, number of affected vessel(single vessel disease), CTO lesion, heart rate, ECG findings, presence of anginal pain, presence of dyspnea , usage of medications ( ACEI and Clopidogrel),hyper urecemia and the time between presentation of complaints and PCI were correlated with improvement of left ventricular function after revascularization by PCI.

Conclusion: Time between appearance of symptoms and PCI was found to be independent predictor of LV EF improvement after revascularization. Other predictors were Male gender, DM, CKD, normal ECG finding ,absence of hyper urecemia, slower heart rate ,presence of chest pain and dyspnea , absence of CTO lesion , single vessel affection and administration of ACEI and Clopidogrel.