VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons

Wozny, Christian and Beed, Prateep and Nitzan, Noam and Pössnecker, Yona and Rost, Benjamin R. and Schmitz, Dietmar (2018) VGLUT2 Functions as a Differential Marker for Hippocampal Output Neurons. Frontiers in Cellular Neuroscience, 12. ISSN 1662-5102

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Abstract

The subiculum is the gatekeeper between the hippocampus and cortical areas. Yet, the lack of a pyramidal cell-specific marker gene has made the analysis of the subicular area very difficult. Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for Channelrhodopsin-2 (ChR2)-assisted connectivity analysis.

Item Type: Article
Subjects: Science Repository > Medical Science
Depositing User: Managing Editor
Date Deposited: 30 May 2023 11:10
Last Modified: 21 Nov 2023 05:06
URI: http://research.manuscritpub.com/id/eprint/2331

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