Coleman, Margaret E. and North, D. Warner and Dietert, Rodney R. and Stephenson, Michele M. (2021) Examining Evidence of Benefits and Risks for Pasteurizing Donor Breastmilk. Applied Microbiology, 1 (3). pp. 408-425. ISSN 2673-8007
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Abstract
An evidence map is visualized as a starting point for deliberations by trans-disciplinary stakeholders, including microbiologists with interests in the evidence and its influence on health and safety. Available evidence for microbial benefits and risks of the breastmilk ecosystem was structured as an evidence map using established risk analysis methodology. The evidence map based on the published literature and reports included the evidence basis, pro- and contra-arguments with supporting and attenuating evidence, supplemental studies on mechanisms, overall conclusions, and remaining uncertainties. The evidence basis for raw breastmilk included one benefit–risk assessment, systematic review, and systematic review/meta-analysis, and two cohort studies. The evidence basis for benefits was clear, convincing, and conclusive, with supplemental studies on plausible mechanisms attributable to biologically active raw breastmilk. Limited evidence was available to assess microbial risks associated with raw breastmilk and pasteurized donor milk. The evidence map provides transparent communication of the ‘state-of-the-science’ and uncertainties for microbial benefits and risks associated with the breastmilk microbiota to assist in deeper deliberations of the evidence with decision makers and stakeholders. The long-term aims of the evidence map are to foster deliberation, motivate additional research and analysis, and inform future evidence-based policies about pasteurizing donor breastmilk.
Item Type: | Article |
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Subjects: | Science Repository > Biological Science |
Depositing User: | Managing Editor |
Date Deposited: | 25 Nov 2022 04:36 |
Last Modified: | 18 Sep 2023 10:37 |
URI: | http://research.manuscritpub.com/id/eprint/272 |