Immunotherapeutic Activities of a DNA Plasmid Carrying the Mycobacterial hsp65 Gene (DNAhsp65)

Silva, Celio Lopes and Malardo, Thiago and Tahyra, Aline Seiko Carvalho (2020) Immunotherapeutic Activities of a DNA Plasmid Carrying the Mycobacterial hsp65 Gene (DNAhsp65). Frontiers in Medical Technology, 2. ISSN 2673-3129

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Official URL: https://doi.org/10.3389/fmedt.2020.603690

Abstract

DNA vaccines have become relevant subject matter, and efforts for their development have been increasing due to their potential as technology platforms applicable for prophylactic and therapeutic approaches for infectious diseases and for cancer treatment, allergies, and autoimmune diseases. This review aimed to summarize current knowledge about the plasmid DNA vaccine carrying the mycobacterial hsp65 gene (DNAhsp65), which demonstrates immunomodulatory and immunoregulatory properties of both the innate and adaptive immune systems. The possible mechanisms associated with the modulation and regulatory role of DNAhsp65 in the control of various conditions is also discussed.

Item Type:	Article
Subjects:	Science Repository > Medical Science
Depositing User:	Managing Editor
Date Deposited:	18 Jan 2023 10:28
Last Modified:	01 Sep 2023 04:28
URI:	http://research.manuscritpub.com/id/eprint/317

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