Hajib, Sara and Aouine, Younas and Alami, Anouar and Faraj, Hassane and Hallaoui, Abdelilah El (2020) Synthesis, Characterization and Antibacterial Activity study of 4-[(1H-pyrazol-1-yl)methyl]-4- methyl-2-phenyl-4,5-dihydrooxazole. B P International. ISBN 978-93-89816-77-8
Full text not available from this repository.Abstract
The N-alkylation of O-tosyloxazoline 1 and a pyrazole compound 2 in the presence of KOH as base in
DMSO at 80°C leads to the formation of the compound 4-[(1H-pyrazol-1-yl)methyl]-4-methyl-2-phenyl-
4,5-dihydrooxazole 3. The structure of the synthesized compound was established on the basis of
NMR spectroscopy (1H, 13C) and MS data. The synthesized product was tested in vitro for
antibacterial activity against Gram-positive and Gram-negative bacteria (S. aureus, B. subtilis,
Streptococcus, P. aeruginosa, E. coli).
| Item Type: | Book |
|---|---|
| Subjects: | Science Repository > Chemical Science |
| Depositing User: | Managing Editor |
| Date Deposited: | 15 Nov 2023 07:04 |
| Last Modified: | 15 Nov 2023 07:04 |
| URI: | http://research.manuscritpub.com/id/eprint/3555 |
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