Immunohistochemistry Analysis of Animals with Post-Ischemic Stroke Treated with LED

Fonseca, Eliane Gonçalves de Jesus and Moreira, Felipe Figueiredo and Dorigoni Bini, Ana Carolina and Cordeiro, Maria Elvira Ribeiro and Hosni, Andressa Panegalli and Razera, Amanda and Tyski Suckow, Patricia Pacheco and Julik, Angela Dubiela and Lopes, Josiane and Kerppers, Ivo Ilvan and Carraro, Emerson (2023) Immunohistochemistry Analysis of Animals with Post-Ischemic Stroke Treated with LED. Journal of Advances in Medicine and Medical Research, 35 (24). pp. 219-227. ISSN 2456-8899

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Abstract

Objective: To evaluate the effects of 630nm LED and 904nm LED in animals subjected to ischemic stroke, using the immunohistochemistry of these animals as analysis parameters.

Methodology: The present work presents an experimental study with a controlled intervention that included 75 male Wistar rats. The animals were allocated into three groups: a control group consisting of 15 animals without treatment, a group treated with 630nm LED, and a group treated with0 904nm LED, composed of 30 animals each. All animals underwent stereotaxic surgery for electrode implantation and subsequent electrolyte injury. The results were compared on days 3, 7, and 21 of treatment after surgery.

Results: The immunohistochemical analysis showed an improvement in the inflammatory response and tissue repair of the animals of both groups treated.

Conclusion: The present study suggests that the treatments with 630nm LED and 904nm LED favored a significant response, which may be a promising technique because of its simplicity, low cost, and easy application.

Item Type: Article
Subjects: Science Repository > Medical Science
Depositing User: Managing Editor
Date Deposited: 09 Jan 2024 05:09
Last Modified: 09 Jan 2024 05:09
URI: http://research.manuscritpub.com/id/eprint/3881

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