Effects of Pharmaceutical Substances with Obesogenic Activity on Male Reproductive Health

Mascarenhas, Caio and Sousa, Ana C. A. and Rato, Luís (2024) Effects of Pharmaceutical Substances with Obesogenic Activity on Male Reproductive Health. International Journal of Molecular Sciences, 25 (4). p. 2324. ISSN 1422-0067

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Abstract

Obesogens have been identified as a significant factor associated with increasing obesity rates, particularly in developed countries. Substances with obesogenic traits are prevalent in consumer products, including certain pharmaceuticals. Specific classes of pharmaceuticals have been recognized for their ability to induce weight gain, often accompanied by hormonal alterations that can adversely impact male fertility. Indeed, research has supplied evidence underscoring the crucial role of obesogens and therapeutic agents in the normal functioning of the male reproductive system. Notably, sperm count and various semen parameters have been closely linked to a range of environmental and nutritional factors, including chemicals and pharmacological agents exhibiting obesogenic properties. This review aimed to explore studies focused on analyzing male fertility parameters, delving into the intricacies of sperm quality, and elucidating the direct and adverse effects that pharmacological agents may have on these aspects.

Item Type: Article
Subjects: Science Repository > Multidisciplinary
Depositing User: Managing Editor
Date Deposited: 16 Feb 2024 05:58
Last Modified: 16 Feb 2024 05:58
URI: http://research.manuscritpub.com/id/eprint/3971

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