MUTAGENIC EFFECT OF SODIUM VALPORATE ON BONE MARROW CELLS OF MICE EVALUATED BY MICRONUCLEUS METHOD

VIJAYALAXMI, K. K. and RAHIMAN, M. ABDUL (1989) MUTAGENIC EFFECT OF SODIUM VALPORATE ON BONE MARROW CELLS OF MICE EVALUATED BY MICRONUCLEUS METHOD. BIONATURE, 9 (1). pp. 21-23.

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Abstract

The mutagenic effect of sodium valproate, an antiepileptic agent was investigated by using mouse bone marrow micronucleus test. The drug was administered intraperitoneally to experimental animals at doses of 26.66, 133.0 and 266.6 mg/kg body weight. Bone marrow micronucleus preparations were made at different time intervals. The drug induced statistically significant micronuclei at higher doses.

Item Type: Article
Subjects: Science Repository > Biological Science
Depositing User: Managing Editor
Date Deposited: 29 Jun 2024 09:32
Last Modified: 29 Jun 2024 09:32
URI: http://research.manuscritpub.com/id/eprint/4204

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