Uchida, Tomoko and Matsuzawa, Daisuke and Shiohama, Tadashi and Fujii, Katsunori and Shiina, Akihiro and Naka, Masamitsu and Sugita, Katsuo and Shimizu, Eiji and Shimojo, Naoki and Hamada, Hiromichi (2024) Positive Effect of Transcranial Direct Current Stimulation on Visual Verbal Working Memory in Patients with Attention-Deficit/Hyperactivity Disorder. Open Journal of Psychiatry, 14 (04). pp. 334-346. ISSN 2161-7325
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Abstract
Background: Working memory is an executive function that plays an important role in many aspects of daily life, and its impairment in patients with attention-deficit/hyperactivity disorder (ADHD) affects quality of life. The dorsolateral prefrontal cortex (DLPFC) has been a good target site for transcranial direct current stimulation (tDCS) due to its intense involvement in working memory. In our 2018 study, tDCS improved visual-verbal working memory in healthy subjects. Objective: This study examines the effects of tDCS on ADHD patients, particularly on verbal working memory. Methods: We conducted an experiment involving verbal working memory of two modalities, visual and auditory, and a sustained attention task that could affect working memory in 9 ADHD patients. Active or sham tDCS was applied to the left DLPFC in a single-blind crossover design. Results: tDCS significantly improved the accuracy of visual-verbal working memory. In contrast, tDCS did not affect auditory-verbal working memory and sustained attention. Conclusion: tDCS to the left DLPFC improved visual-verbal working memory in ADHD patients, with important implications for potential ADHD treatments.
Item Type: | Article |
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Subjects: | Science Repository > Medical Science |
Depositing User: | Managing Editor |
Date Deposited: | 19 Jul 2024 10:44 |
Last Modified: | 19 Jul 2024 10:44 |
URI: | http://research.manuscritpub.com/id/eprint/4223 |