Serum lipid abnormalities in type 2 diabetes mellitus

Aim: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin. The present study was conducted to determine the lipid profile of diabetes in Delta State.

Methods: Serum total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL) as well as Body mass index (BMI) were determined in two hundred subjects. One hundred were diabetic and the other one hundred were apparently healthy individuals used as controls.

Results: The TC, TG, LDL-C, VLDL-C as well as BMI of diabetes were observed to be significantly high (P<0.05) when compared with control subjects. HDL-C in diabetes was observed to be significantly low (P<0.05) when compared with control subjects.

Conclusion: The result indicates dyslipidemia in diabetes. Adequate and proper management of diabetes to reduce dyslipidemia and further complications are therefore recommended.