Programmed cell death 1 ligand (PD-L1) on T cells generates Treg suppression from memory

Kazanova, Alexandra and Rudd, Christopher E. (2021) Programmed cell death 1 ligand (PD-L1) on T cells generates Treg suppression from memory. PLOS Biology, 19 (5). e3001272. ISSN 1545-7885

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Abstract

A recent study shows that programmed cell death 1 ligand (PD-L1) on activated T cells promotes their conversion to suppressive inducible regulatory T cells (iTregs), preferentially from among memory T cells. This new mechanism may normally protect against autoimmunity but is dysregulated in rheumatoid arthritis.

Item Type: Article
Subjects: Science Repository > Biological Science
Depositing User: Managing Editor
Date Deposited: 25 Jan 2023 05:01
Last Modified: 16 Jul 2024 06:47
URI: http://research.manuscritpub.com/id/eprint/948

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