Linac Based Stereotactic Radiosurgery as Salvage Treatment in Primary Central nervous System Lymphoma- a Case Report

Primary central nervous system lymphoma (PCNSL) is a rare form of extranodal non-hodgkin lymphoma that is confined to the central nervous system. The treatment includes induction chemotherapy followed by whole brain radiation. However, the prognosis is dismal and residual or refractory disease is very common with not many options available to treat such cases. Stereo-tactic radiosurgery (SRS) is evolving to salvage small volume tumors in younger age and good performance status patients. With the limited facility and experience of linac based or Gamma knife SRS, there are sparse reports for such cases from the Indian sub-continent. We report our first case from our institution treated by linac based SRS in a case of refractory PCNSL.